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15.Jul.2018

Research and Journals

eferences(Journal articles/research reports)

一. In 1958, Odland discovered that when the wound develops blisters, if we keep blisters unbroken, then the healing speed of the wounds are faster. G.F. Odland“. The fine structure of the interrelationship of cells in the human epidermis.” J. Biophys Biochem Cytol, vol. 4, pp.529-538,1958.)


二. In 1962, Winter conducted an animal experiment and covered a polyurethane (PU) waterproof film on wounds to keep the wounds moist. The results showed that the moist wounds healed faster. (G.D. Winter“. Formation of the scab and the rate of epithelization of superficial wounds in the skin of the young domestic pig.” Nature, vol. 193, pp. 293-294, 1962.)


三.In 1963, Hinman and Maibnch further confirmed with human experiments that wet wounds on human bodies also heal faster than dry wounds. Based on these research results, we can see that moist healings are indeed better than dry Healings. It subverted people's old ideas.(C.D. Hinman, H. Maibach. Effect of air exposure and occlusion on experimental human skin wounds. Nature, vol. 200, pp. 377-378, 1963.)


四.In 1972, Rovee had an experiment that he asked for six volunteers and peeled off their skin stratum corneumby by tapes and then the wounds were divided into two areas. One area of the wounds was exposed to dry air and the other area of the wounds was covered with an airtight film to keep it moist. After observing and comparing the recovery processes of the wounds on both areas, it was found that the area covered with a thin film showed a clean, no encrusted wound and its epithelial cell movement was more active and the rate of mitotic hyperplasia was faster. It took about 7 to 10 days to heal the wounds. In contrast to a dry healing wound of the same degree, the encrusted wounds took 12 to 14 days to heal. It has been proven that the healing speed of wounds can be accelerated in a moist environment. Therefore, the concept of moist healing has begun to be widely used. After decades of research, it is now recognized that the healing speed of moist wounds is about 1.5 times faster than that of dry wounds.
 
 
(D.T. Rovee, C.A.Kurowsky, Labun J. Local wound environment and epider-mal healing. Mitotic response. Arch Dermatol, vol. 106, pp.330-334, 1972.)



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